7 Stacks to Increase the Potency of Modafinil


What is Modafinil?

Modafinil is an extremely powerful nootropic, however, it is frequently used in nootropic combinations, known as “stacks,” to enhance its effects even further. Research has shown an increase in the cognitive abilities, efficiency, and productivity of individuals. The study covers the benefits of Modafinil on the human body. They are listed as below:

  • Enhanced mood and alertness

  • Increased motivation

  • Improved reaction time

  • Reduced fatigue

  • Better memory

Modafinil is used by students, shift workers, businessmen and all those who are interested in increasing mental performance. 

This article would be focusing on outlining how the potency of Modafinil can be increased, and benefits using it in different stacks.

Modafinil and Ashwagandha

Photo by mirzamlk/iStock / Getty Images

Photo by mirzamlk/iStock / Getty Images

Essential for making you relaxed and boosting creative thinking. Ashwagandha is an ancient herb beneficial for treating anxiety, stress, fatigue, and pain. The stack effect of Modafinil and Ashwagandha has proven to be really helpful. The results allow the individual to work productively throughout the day and fight the anxiety levels more easily given by the modafinil.  Ashwagandha allows the body to detach from the external environment and provide relief from stress. The Indian herb effects are slow and steady. It is one of the best combinations to be taken along with the Modafinil.

Modafinil and Bacopa

Bacopa is an Indian plant which helps to treat memory issues. The right amount of Modafinil Bacopa stack enhances human thinking power becoming a strong combination for learning, retention and memorization. Bacopa Monnieri is the perfect memory supplement and also an excellent remedy for side effects of modafinil. 

Modafinil and Caffeine


This combination is very famous almost in every part of the world. The dose of Modafinil can be taken early in the morning and coffee can be consumed later to balance the effects of the stack. 

This way the Modafinil helps in increasing the brain performance and the overall productivity and the caffeine helps in the wakefulness and energy boost.  The effect of Modafinil lasts longer on the brain, whereas caffeine is a short-term effector. This makes them a right combination of nootropic stack. 

The disadvantages Modafinil Caffeine stack is the diuretic effect on the individual. It can cause dehydration and a sense of jitter. This must be treated by taking the dose on proper time.  

Modafinil and Piracetam


This is acetylcholine drug that helps in increasing brain activity, blood flow and oxygen consumption in the body. The Racetams are responsible for expanding the mood senses and focus improvement.
The only disadvantage of the combination is that it can make the body feel discouraged and utterly exhausted at the end of the day. With the help of Choline addition to the stack, this disadvantage can be converted into an advantage. 

Modafinil and Noopept


Noopept is known as a cognitive enhancer. It should be consumed with total care in small doses. It is more effective and powerful in comparison with the Piracetam. It helps in strengthening the learning capabilities, thinking skills, and focus. But studies also point out the fact that Noopept can lead to apoptosis and oxidative stress.

When the two nootropics are combined the user experiences increased motivation levels, improved memory recall, alertness and mental clarity with anything the user does. 

This consumption is occasionally advised when the individual needs large focus during the work. It is essential to keep the dosages small to start with and build them up as necessary as it can lead to complete exhaustion of the body. 

Modafinil and Phenibut


Phenibut is a "smart pill" that is used for anxiety, fear, and fatigue, also to prevent fogginess and depression. Modafinil has side effects like anxiety and insomnia, and these side effects are well managed by the Phenibut. This makes the perfect combination.

The benefit is that the person can work during the day and sleep in the night without facing any problems. Modafinil Phenibut stack gives tolerance power and becomes perfect for social engagements. It is advisable to use this drug once a week, but always consult with your physician

Modafinil and L-Theanine


This combination has mixed reviews from the nootropic stack fans. While many say that the combination is not that effective, some are impressed by the effects on cognitive function. 

L-theanine is a component that is found in small proportions in the tea leaves. The stimulant helps in relaxation of the body. Due to a characteristic of the L-Theanine, the body goes into a slow pace, and the level of effectiveness is barely visible.

Some of the side effects of consuming Modafinil is that the individual starts feeling jittery and anxious. L-Theanine is a component which really helps in fighting these side effects. Modafinil L-Theanine stack is perfect for boosting your brain while staying composed and collected.

Modafinil and Choline


Consuming Modafinil Choline stack is known to create wonders. It is capable of boosting the mobility of the brain synopsis network. Choline is an essential nutrient for the development of, and neurotransmitter production in the brain is present in many plants and animal organs. Modafinil is improving the cognitive abilities of the individual along with the productivity.

The combination is so helpful that many receivers report that it helps to fight a migraine and headaches caused by the Modafinil. The problem of feeling lazy after having lunch or dinner due to the ingestion period is resolved with the help of this stack. The Choline also expands the activity levels of Modafinil and helps in improving its effects. 

Let us now understand the mechanism of Modafinil working on the human body:

Narcolepsy is caused due to lack of orexin and Modafinil works to make it perfect. The Modafinil acts with the neural system and increases the production of histamines in the brain, which boosts focus and alertness.

Increases the production of histamines in the body that helps the individual to stay awake for more extended periods of time. 

Unlike the other drugs that increase the release of dopamine quickly, modafinil blocks the receptors and allows a slow and steady release of Dopamine on the receptors of the synapse system, making it work properly without feeling extremely euphoric at a particular moment and utterly exhaustive at the other.
The effect of Modafinil toches the norepinephrine system of the human brain also. This makes the human mind to stay alert and awake. 

Glutamate in the brain is responsible for improving focus and memory and overall cognitive functioning. Modafinil allows the neurotransmitters to send a signal and glutamate is released in the required amount. The ultimate release helps in supporting the cognitive function improvement, effectiveness, and productivity.  


Results of the combinations listed above may vary due to the individual. The body and genetic mechanism are different for all of us.  A dose for one is not suitable for the other. Always consult your physician before consuming any of the supplements. Also be aware of all side effects.